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Title: Clinical management of patients with advanced Parkinson's disease treated with continuous intestinal infusion of levodopa/carbidopa
Author: Santos García, Diego
Martínez Castrillo, Juan Carlos
Puente Périz, Víctor
Seoane Urgorri, Agustín
Fernández Díez, Servando
Benita León, Vicente
Udaeta Baldivieso, Beatriz
Campolongo Perillo, Antonia
Mariscal Pérez, Natividad
Others: Universitat Oberta de Catalunya (UOC)
Keywords: Advanced Parkinson's disease
Clinical guidelines
Levodopa-carbidopa intestinal gel
Motor fluctuation
Spercutaneous endoscopic gastrostomy
Issue Date: 1-Jun-2016
Publisher: Neurodegenerative disease management
Citation: Santos García, D., Martínez Castrillo, J.C., Puente, V., Seoane Urgorri, A., Fernández Díez, S., Benita León, V., Udaeta Baldivieso, B., Campolongo, A. & Mariscal Pérez, N. (2016). Clinical management of patients with advanced Parkinson's disease treated with continuous intestinal infusion of levodopa/carbidopa. Neurodegenerative disease management, 6(3), 187-202. doi: 10.2217/nmt-2016-0011
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Abstract: Patients with Parkinson's disease often have a good initial response to dopaminergic therapy but later usually develop motor fluctuations and dyskinesia. In these patients, continuous infusion of levodopa-carbidopa intestinal gel (LCIG) allows for maintaining adequate dopamine levels and for improving motor and nonmotor symptoms, as well as quality of life and autonomy. Adequate candidate selection and follow-up are crucial for treatment success. Management should be multidisciplinary, and patient and caregiver education is a priority. This expert consensus document has been developed by a team of neurologists, gastroenterologists and nurses who have a vast experience in LCIG therapy, with an intention to provide knowledge and tools to facilitate patient management throughout all phases of LCIG treatment process.
Language: English
ISSN: 1758-2024MIAR

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