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Title: PET Scan: Nuclear Medicine Imaging in Myositis
Author: Selva O'Callaghan, Albert
Gil Vila, Albert
Simó Perdigó, Marc
Trallero Araguás, Ernesto
Alvarado Cárdenas, Marcelo
Pinal Fernández, Iago
Others: Johns Hopkins University School of Medicine
Universitat Autònoma de Barcelona
Universitat Oberta de Catalunya (UOC)
Keywords: PET/CT
Sporadic inclusion body myositis
Issue Date: 21-Nov-2019
Publisher: Current Rheumatology Reports
Citation: Selva-O'Callaghan, A., Gil-Vila, A., Simó-Perdigó, M., Trallero-Araguás, E., Alvarado-Cárdenas, M. & Pinal-Fernández, I. (2019). PET Scan: Nuclear Medicine Imaging in Myositis. Current Rheumatology Reports, 21(11), 1-8. doi: 10.1007/s11926-019-0864-3
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Abstract: Purpose of Review Positron emission tomography (PET) combined with computed tomography (CT) has proven useful as a cancer screening technique in patients with inflammatory myopathy, mainly dermatomyositis. In this review, we focus on advances in this direction and other potential applications of PET/CT in patients with inflammatory myopathy. Recent Findings Cancer screening by PET/CT seems suitable and cost-effective in patients with myositis. It has also shown value as a hybrid technique for diagnosing myositis versus controls and could be of interest for differentiating between polymyositis and sporadic inclusion body myositis. Quantification of muscle activity by PET/CT seems reliable. Preliminary data suggest that it could also be used to diagnose and measure the activity of the disease in the lung. Summary PET/CT should be in the toolbox of physicians managing patients with myositis. The multiple applications of PET/CT include its value for cancer screening, measuring the activity of the disease in muscle, and helping to differentiate between myositis phenotypes. The possibility to diagnose and monitor inflammatory lung activity remains to be demonstrated in welldesigned studies.
Language: English
ISSN: 1523-3774MIAR
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