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http://hdl.handle.net/10609/64246
Title: Búsqueda de SNPs y CNVs en Leishmania donovani
Author: Camacho Cano, Esther
Director: Olivares Castiñeira, Ivette
Tutor: Ventura Royo, Carles  
Others: Universitat Oberta de Catalunya
Keywords: SNP
resistance
Leishmania
Issue Date: May-2017
Publisher: Universitat Oberta de Catalunya
Abstract: In this TFM, four drug resistant lines, together with the parental line of Leishmania donovani HU3 strain, have been studied. In order to evaluate genomic alterations, a CNVs search along the genomes was carried out; several somy changes between resistant lines and the parental line have been evidenced. Also, CNVs searches have been done at the chromosomal level by comparing the reads coverage, within discrete chromosomal windows, in the resistant lines regarding the parental one. As a result, 377 CNVs were identified.
Language: Spanish
URI: http://hdl.handle.net/10609/64246
Appears in Collections:Bachelor thesis, research projects, etc.

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esther_camachoTFM0617memoria.pdfMemoria del trabajo fin de máster2.65 MBAdobe PDFView/Open
esther_ camachoTFM0617anexos.pdfAnexos de la memoria del TFM6.72 MBAdobe PDFView/Open

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