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Title: Búsqueda de dianas genéticas como polimorfismos (SNPs) en genes asociados a la enfermedad neurodegenerativa del Alzheimer
Author: Barruz Galián, María del Pilar
Director: Olivares Castiñeira, Ivette
Tutor: Ventura Royo, Carles  
Others: Universitat Oberta de Catalunya
Keywords: SNP
Issue Date: 5-Jun-2018
Publisher: Universitat Oberta de Catalunya
Abstract: Alzheimer's is the most common dementia. Mainly a progressive cognitive and neurodegenerative loss characcteriza Alzheimer´s disease. Epidemiologically, Alzheimer represents a problem since in the middle of the 21st century it will constitute a socio-sanitary problem and it will be an index of mortality, so it is essential to be able to determine the etiology of the disease. In order to molecularly assess Alzheimer's disease, the following study was carried out, selecting from Gene Expression Omnibus (from dataset GSE84422) six tissues from different cortical and subcortical regions, pathognomonicly related to Alzheimer's. Genes have been detected with the three methods of analysis proposed and, some others, are associated with the neurodegenerative disease of Alzheimer.
Language: Spanish
Appears in Collections:Bachelor thesis, research projects, etc.

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