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http://hdl.handle.net/10609/84305
Title: Trastornos emocionales y conductuales en accidentes cerebrovasculares: prevalencia, etiología y neuroanatomía
Author: Lázaro Cagigal, Noelia
Director: Aparicio, Celeste
Keywords: emotional and behavior disorders
stroke
acquired brain damage
Issue Date: 16-Jan-2018
Publisher: Universitat Oberta de Catalunya (UOC)
Abstract: Emotional and behavioral disorders occur very frequently after strokes, but research has not given them the importance they deserve. Depression, anxiety, apathy, irritability, behavioral disinhibition, emotionalism and changes in personality, the most common diseases, are a source of distress in both the patient and caregiver, decreasing the productivity of rehabilitation and patient functionality and increasing dependence, making it difficult to reintegrate into the work, social and family life. The knowledge of the prevalence, etiological causes and brain locations associated with each of these deseases can help us to understand how they work, prevent their appearance or warn early to avoid severity. The most studied disorder in this area is post-stroke depression, which is more consistently related to frontal locations and basal ganglia, also related with the hypothalamic-pituitary-adrenal axis, with the increase of proinflammatory cytokines, the decrease of serotonin and its metabolites and with the decrease of BDNF. Anxiety is also related to inflammatory processes typical of stroke and apathy with prefrontal areas (orbitofrontal and dorsolateral cortex) and the limbic system, like anger. In the absence of replicability of the affected brain areas, is currently being chosen to look for the causes in the dysfunction of neuronal networks and specific neurotransmitters. These disorders are closely related to each other and consensus in their description, as well as new tools to evaluate them, are needed for future research. The aim of the present paper is to capture a reliable image of the current situation of these disorders, through an analysis of the most recent bibliography.
Language: Spanish
URI: http://hdl.handle.net/10609/84305
Appears in Collections:Bachelor thesis, research projects, etc.

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