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Title: Efecto de los probióticos en el control de la obesidad en humanos: hipótesis no demostradas
Other Titles: Effects of probiotics on human obesity control: an unproven hypothesis
Author: Arias Pineda, Amparo
Mach Casellas, Núria
Others: Universitat Oberta de Catalunya (UOC)
Keywords: obesity
probiotic
body weight control
metagenome
Issue Date: Nov-2012
Publisher: Revista Española de Nutrición Humana y Dietética
Citation: Arias, A. & Mach, N. (2012). Efecto de los probióticos en el control de la obesidad en humanos: hipótesis no demostradas. Revista Española de Nutrición Humana y Dietética, 16(3), 100-107. doi: 10.1016/S2173-1292(12)70081-9
Also see: http://doi.org/10.1016/S2173-1292(12)70081-9
Abstract: The objective of the present study is to review the different publications associated with probiotics and obesity, as well as to get some new insights regarding the role of the microbiome in diseases such as obesity. An extensive search for scientific publications (studies in animal models, cells, clinical trials and reviews) was performed in the following specialist computer databases (PubMed central (PMC)-NCBI, Elsevier Journal, Scielo Spain, Scirus, Science Direct) to establish the current status of the potential effect of probiotics in the control of obesity in humans, as well as the relationship between intestinal microbiota and obesity. The intestinal microbiota and oral probiotics have a positive effect on human health, as they can regulate the immune functions and protect from infections and chronic inflammatory processes. Although divergent results have recently been reported, it has been shown but not confirmed that intestinal microbiota might play a role as a new factor associated with the regulation of body weight and obesity-related diseases. The international MetaHIT project has shown that human microbiome populations can be grouped into three different enterotypes. Two of these enterotypes (Bacteroides and Ruminococcus) seem to encode functions related to obesity. Although the relationship between intestinal microbiota and obesity are not yet well established, the attempt to manipulate intestinal microbiota through diet is suggested as a new plausible approach to prevent, or modify the risk of, obesity and its related diseases. More clinical studies in humans are required to clarify the possible effect of probiotics on obesity.
Language: Spanish
URI: http://hdl.handle.net/10609/92211
ISSN: 2173-1292MIAR
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