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http://hdl.handle.net/10609/109606
Title: | Búsqueda de nuevas dianas terapéuticas para la esclerosis lateral amiotrófica (ELA) |
Author: | Peral Martínez, Paula |
Tutor: | Romero Cuevas, Miguel |
Others: | Canovas Izquierdo, Javier Luis |
Abstract: | Amyotrophic lateral sclerosis, ALS, is a neurodegenerative disease which involves loss of muscle control. As a result , limb mobility and, as the disease progresses, the ability to eat, breathe and communicate are affected. This disease has a low prevalence due to its high mortality and has a higher incidence between the ages of 40 and 70. This disease has been chosen as the subject because of general ignorance and its high morbidity. An integrated team of doctors and various therapies are used to treat this disease, although they only serve to delay symptomatology and prevent complications. Work will focus on drug therapies as they help alleviate many of the symptoms and increase and increase the life expectancy of patients. The objective of this work is to find new therapeutic targets using computational tools. This could open up new lines of research and perhaps can be found a therapy which involves an improvement in the treatment of ALS. |
Keywords: | amyotrophic lateral sclerosis therapeutic targets |
Document type: | info:eu-repo/semantics/masterThesis |
Issue Date: | Jan-2020 |
Publication license: | http://creativecommons.org/licenses/by-nc-nd/3.0/es/ |
Appears in Collections: | Trabajos finales de carrera, trabajos de investigación, etc. |
Files in This Item:
File | Description | Size | Format | |
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pperalTFM0120memoria.pdf | Memoria del TFM | 3,3 MB | Adobe PDF | View/Open |
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