Please use this identifier to cite or link to this item:
http://hdl.handle.net/10609/151691
Title: | Cognitive profile and cardiovascular risk Factors in older adults with mild cognitive impairment |
Author: | Vázquez De Sebastián, Julia ![]() Ortiz Zúñiga, Ángel Michael ![]() Ciudin Mihai, Andreea ![]() Ars , Joan ![]() Inzitari, Marco ![]() Simó Canonge, Rafael ![]() Hernandez, Cristina ![]() Ariño-Blasco, Sergio ![]() Barahona, Maria-José ![]() Franco-Romero, M ![]() Gironès, Xavier ![]() CRESPO MARAVER, MARIA CRUZ ![]() Carles, Joan ![]() Castellano-Tejedor, Carmina ![]() The DIALCAT Consortium |
Citation: | Vazquez de Sebastián, J. [Julia], Ortiz Zuñiga, A. [Angel], Ciudin, A. [Andreea], Ars, J. [Joan], Inzitari, M. [Marco], Simó, R. [Rafael], Hernández, C. [Cristina], Ariño Blasco, S. [Sergio], Barahona, M.J. [Maria José], Franco, M. [Maite], Gironès, X. [Xavier,] Crespo Maraver, M.C. [María Cruz], Rovira, J.C. [Joan Carles] & Castellano-Tejedor, C. [Carmina]. (2024). Cognitive profile and cardiovascular risk Factors in older adults with mild cognitive impairment. International Journal of Environmental Research and Public Health, 21(4), 1-15. doi: 10.3390/ijerph21040500 |
Abstract: | The prevalence of cardiovascular risk factors (CVRFs) in the older adults population and their specific impact on their cognitive profiles still requires further research. For this purpose, a cross-sectional study was carried out to describe the presence of CVRFs and their association with cognitive performance in a sample of older adults (65–85 years old) with Mild Cognitive Impairment (MCI). Participants (n = 185) were divided into three groups concerning their cardiovascular risk level determined by the presence of different CVRFs, including Type 2 Diabetes (T2D), dyslipidemia, hypertension, and obesity. The primary outcome measures were the participant’s scores in the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS). Sociodemographic, clinical, and psychosocial data were collected. Non-parametrical statistical analyses and effect sizes were calculated. Findings revealed that a greater presence of CVRFs was not associated with a worse overall cognitive performance. High-risk patients were more likely to have significantly worse performance in the attentional domain compared to medium-risk (p = 0.029, r = 0.42) and compared to low-risk (p = 0.041, r = 0.35), specifically in the digits repetition subtest (p = 0.042). T2D alone was the CVRF associated with cognitive differences (p = 0.037, r = 0.32), possibly mediated by the duration of the condition. Consequently, a higher presence of CVRFs did not lead to a worse overall cognitive performance. However, high-risk individuals were more likely to experience cognitive impairment, particularly in the attentional domain. T2D played a significant role in these cognitive profile differences, possibly influenced by its duration. |
Keywords: | cardiovascular risk factors type 2 diabetes cognitive impairment neuropsychological profile mild cognitive impairment older adults |
DOI: | https://doi.org/10.3390/ijerph21040500 |
Document type: | info:eu-repo/semantics/article |
Version: | info:eu-repo/semantics/publishedVersion |
Issue Date: | 18-Apr-2024 |
Publication license: | http://creativecommons.org/licenses/by/3.0/es/ ![]() |
Linked data: | https://mdpi.altmetric.com/details/162650009 |
Appears in Collections: | Articles Articles cientÍfics |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
Vazquez_IJERPH_Cognitive.pdf | 396,54 kB | Adobe PDF | ![]() View/Open |
Share:


This item is licensed under aCreative Commons License