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http://hdl.handle.net/10609/63805
Title: | Bioinformática y Biología: Investigación sobre el desarrollo de nuevos ARNm como posibles marcadores de la LLC y su relación con el estrés oxidativo |
Author: | Romero Fernández-Bravo, Miguel Ángel |
Tutor: | Rosich, Laia |
Others: | Universitat Oberta de Catalunya Perez-Navarro, Antoni Merino, David |
Abstract: | The application of bioinformatics tools to study cancer aids the understanding of their genetic origins. This study involved chronic lymphocytic leukaemia (CLL), a haematological malignancy of B-lymphocytes. BIRC3 and POT1 are two genes mutated in patients with CLL. This paper focuses on the search for homologues to these genes as possible markers of CLL. A search of genes associated with CLL returned HIV-1 sequences in cancer associated genes: BIRC3, POT1, PT53 and OXSR1. Oxidative stress may be an underlying factor since it is associated with a range of malignancies, including OXSR1 gene in patients with CLL. |
Keywords: | CLL HIV-1 oxidative stress |
Document type: | info:eu-repo/semantics/masterThesis |
Issue Date: | 24-May-2017 |
Publication license: | http://creativecommons.org/licenses/by-nc-nd/3.0/es/ |
Appears in Collections: | Trabajos finales de carrera, trabajos de investigación, etc. |
Files in This Item:
File | Description | Size | Format | |
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mromerofernTFM0617memoria.pdf | Memoria del trabajo fin de máster | 21,35 MB | Adobe PDF | View/Open |
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