Please use this identifier to cite or link to this item: http://hdl.handle.net/10609/64246
Title: Búsqueda de SNPs y CNVs en Leishmania donovani
Author: Camacho Cano, Esther
Tutor: Ventura, Carles  
Others: Universitat Oberta de Catalunya
Ventura, Carles  
Keywords: SNP
resistance
Leishmania
Issue Date: May-2017
Publisher: Universitat Oberta de Catalunya
Abstract: In this TFM, four drug resistant lines, together with the parental line of Leishmania donovani HU3 strain, have been studied. In order to evaluate genomic alterations, a CNVs search along the genomes was carried out; several somy changes between resistant lines and the parental line have been evidenced. Also, CNVs searches have been done at the chromosomal level by comparing the reads coverage, within discrete chromosomal windows, in the resistant lines regarding the parental one. As a result, 377 CNVs were identified.
Language: Spanish
URI: http://hdl.handle.net/10609/64246
Appears in Collections:Trabajos finales de carrera, trabajos de investigación, etc.

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esther_camachoTFM0617memoria.pdfMemoria del trabajo fin de máster2,65 MBAdobe PDFThumbnail
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esther_ camachoTFM0617anexos.pdfAnexos de la memoria del TFM6,72 MBAdobe PDFThumbnail
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