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http://hdl.handle.net/10609/127070
Title: | Análisis de la supervivencia y de sus factores pronóstico en pacientes tratados de compresión medular metastásica en el Instituto Catalán de Oncología |
Author: | Jordi Ollero, Olivia |
Tutor: | Fernández Martínez, Daniel |
Others: | Maceira, Marc |
Abstract: | The goal of this paper is twofold. On the one hand, we want to compare the survival of patients affected by spinal cord compression (CM) treated at the Catalan Institute of Oncology recruited prior to 2018 with the survival of those who were recruited from that year on. On the other hand, we want to study which factors could be prognostic of survival. Using the Kaplan-Meier estimator, the survival curves of the entire sample and the groups discussed above have been found. Univariate and multivariate Cox regressions have been carried out, as well as machine learning modeling using decision trees, Random Forest and GBM that have been validated on a set of data. It was not possible to establish differences in the survival of the two groups of patients. Resulting variables for survival prognosis were oncologic treatment after spine cord compression treatment was finished, Rades index, ambulatory status at 7 days and not having previously performed decompressive radiotherapy. The best performing model was Cox regression. |
Keywords: | tumour biomarker RADES, SINS and Blisky scales multidisciplinary approach |
Document type: | info:eu-repo/semantics/masterThesis |
Issue Date: | 5-Jan-2021 |
Publication license: | http://creativecommons.org/licenses/by-nc/3.0/es/ |
Appears in Collections: | Trabajos finales de carrera, trabajos de investigación, etc. |
Files in This Item:
File | Description | Size | Format | |
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ojordiTFM0121memoria.pdf | Memoria del TFM | 6,21 MB | Adobe PDF | View/Open |
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