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http://hdl.handle.net/10609/63805
| Title: | Bioinformática y Biología: Investigación sobre el desarrollo de nuevos ARNm como posibles marcadores de la LLC y su relación con el estrés oxidativo |
| Author: | Romero Fernández-Bravo, Miguel Ángel |
| Tutor: | Rosich, Laia  |
| Others: | Universitat Oberta de Catalunya Pérez Navarro, Antoni Merino, David |
| Keywords: | CLL HIV-1 oxidative stress |
| Issue Date: | 24-May-2017 |
| Publisher: | Universitat Oberta de Catalunya |
| Abstract: | The application of bioinformatics tools to study cancer aids the understanding of their genetic origins. This study involved chronic lymphocytic leukaemia (CLL), a haematological malignancy of B-lymphocytes. BIRC3 and POT1 are two genes mutated in patients with CLL. This paper focuses on the search for homologues to these genes as possible markers of CLL. A search of genes associated with CLL returned HIV-1 sequences in cancer associated genes: BIRC3, POT1, PT53 and OXSR1. Oxidative stress may be an underlying factor since it is associated with a range of malignancies, including OXSR1 gene in patients with CLL. |
| Language: | |
| URI: | http://hdl.handle.net/10609/63805 |
| Appears in Collections: | Trabajos finales de carrera, trabajos de investigación, etc. |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| mromerofernTFM0617memoria.pdf | Memoria del trabajo fin de máster | 21,35 MB | Adobe PDF |  View/Open |
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