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Campo DC | Valor | Lengua/Idioma |
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dc.contributor.author | Romera Liebana, Laura | - |
dc.contributor.author | Orfila, Francesc | - |
dc.contributor.author | Segura, Josep Maria | - |
dc.contributor.author | Real, Jordi | - |
dc.contributor.author | Fabra, Maria Lluïsa | - |
dc.contributor.author | Möller, Mercedes | - |
dc.contributor.author | Lancho, Santiago | - |
dc.contributor.author | Ramirez, Anna | - |
dc.contributor.author | Martí, Núria | - |
dc.contributor.author | Cullell, Montserrat | - |
dc.contributor.author | Bastida, Núria | - |
dc.contributor.author | Martinez, Dolors | - |
dc.contributor.author | Giné Garriga, Maria | - |
dc.contributor.author | Cendrós Ramirez, Patricia | - |
dc.contributor.author | Bistuer Lacarra, Ana | - |
dc.contributor.author | Pérez, Elena | - |
dc.contributor.author | Fabregat Casamitjana, Maria Assumpta | - |
dc.contributor.author | Foz Gil, Gonçal | - |
dc.contributor.other | Institut Català de la Salut | - |
dc.contributor.other | Universitat Autònoma de Barcelona (UAB) | - |
dc.contributor.other | Universitat Ramon Llull | - |
dc.contributor.other | Universitat Oberta de Catalunya (UOC) | - |
dc.date.accessioned | 2019-04-15T11:37:13Z | - |
dc.date.available | 2019-04-15T11:37:13Z | - |
dc.date.issued | 2018-01-16 | - |
dc.identifier.citation | Romera-Liebana, L., Orfila, F., Segura, J. M., Real, J., Fabra, M. L., Möller, M., . . . Foz, G. (2018). Effects of a primary care-based multifactorial intervention on physical and cognitive function in frail, elderly individuals: A randomized controlled trial. Journals of Gerontology - Series A Biological Sciences and Medical Sciences, 73(12), 1668-1674. doi:10.1093/gerona/glx259 | en |
dc.identifier.issn | 1079-5006MIAR | - |
dc.identifier.issn | 1758-535XMIAR | - |
dc.identifier.uri | http://hdl.handle.net/10609/93194 | - |
dc.description.abstract | Background: Detecting and managing frailty at early stages can prevent disability and other adverse outcomes. The study aim was to evaluate whether a multifactorial intervention program could modify physical and cognitive frailty parameters in elderly individuals. Methods: We conducted a multicenter, randomized, single-blind, parallel-group trial in community-living prefrail/frail elderly individuals in Barcelona. A total of 352 patients, aged ¿65 years old with positive frailty screening, was randomized into two groups to receive a 12-week multidisciplinary intervention or usual care, with concealed allocation. The intervention consisted of: exercise training, intake of hyperproteic nutritional shakes, memory training, and medication review. Main outcome assessments with multivariate analysis were conducted at 3 and 18 months. Results: A total of 347 participants (98.6%) completed the study, mean age 77.3 years, 89 prefrail subjects (25.3%), and 75.3% female (n = 265). Eighteen-month assessments were performed in 76% of the sample. After 3 and 18 months, adjusted means difference between-groups showed significant improvements for the intervention group in all comparisons: Short Physical Performance Battery score improved 1.58 and 1.36 points (p < .001), handgrip strength 2.84 and 2.49 kg (p < .001), functional reach 4.3 and 4.52 cm (p < .001), and number of prescriptions decreased 1.39 and 1.09 (p < .001), respectively. Neurocognitive battery also showed significant improvements across all dimensions at 3 and 18 months. Conclusions: A physical, nutritional, neurocognitive, and pharmacological multifaceted intervention was effective in reversing frailty measures both at short-term and 18 months. Lasting benefits of a multi-intervention program among frail elderly individuals encourage its prioritization. | en |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | The journals of gerontology. Series A, Biological sciences and medical sciences | - |
dc.relation.uri | https://academic.oup.com/biomedgerontology/article-pdf/73/12/1668/26677503/glx259.pdf | - |
dc.rights | implied-oa | - |
dc.title | Effects of a Primary Care-Based Multifactorial Intervention on Physical and Cognitive Function in Frail, Elderly Individuals: A Randomized Controlled Trial | - |
dc.type | info:eu-repo/semantics/article | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.doi | 10.1093/gerona/glx259 | - |
dc.gir.id | AR/xxx | - |
dc.type.version | info:eu-repo/semantics/publishedVersion | - |
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