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http://hdl.handle.net/10609/101699
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DC Field | Value | Language |
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dc.contributor.author | Martín Cardona, Albert | - |
dc.contributor.author | Fernández Esparrach, Gloria | - |
dc.contributor.author | Súbtil Íñigo, José Carlos | - |
dc.contributor.author | Iglesias García, Julio | - |
dc.contributor.author | García Guix, Marta | - |
dc.contributor.author | Barturen Barroso, Angel | - |
dc.contributor.author | Gimeno García, Antonio Z. | - |
dc.contributor.author | Esteban, José Miguel | - |
dc.contributor.author | Pardo Balteiro, Albert | - |
dc.contributor.author | Velasco Guardado, Antonio | - |
dc.contributor.author | Vazquez Sequeiros, Enrique | - |
dc.contributor.author | LORAS ALASTRUEY, CARME | - |
dc.contributor.author | Martínez Moreno, Belén | - |
dc.contributor.author | Castellot Martín, Ana | - |
dc.contributor.author | Huertas Nadal, Carlos | - |
dc.contributor.author | Martínez Lapiedra, Mamen | - |
dc.contributor.author | Sánchez Yague, Andrés | - |
dc.contributor.author | Teran, Álvaro | - |
dc.contributor.author | Morales Alvarado, Víctor J. | - |
dc.contributor.author | Betés Ibáñez, Maria Teresa | - |
dc.contributor.author | Iglesia, Daniel de la | - |
dc.contributor.author | Sánchez Montes, Cristina | - |
dc.contributor.author | Lozano Escario, María Dolores | - |
dc.contributor.author | Lariño Noia, José | - |
dc.contributor.author | Ginès, Àngels | - |
dc.contributor.author | Tebe, Cristian | - |
dc.contributor.author | gornals, joan b | - |
dc.contributor.other | Universitat Oberta de Catalunya (UOC) | - |
dc.date.accessioned | 2019-10-16T07:38:33Z | - |
dc.date.available | 2019-10-16T07:38:33Z | - |
dc.date.issued | 2019-06-06 | - |
dc.identifier.citation | Martín-Cardona, A., Fernández-Esparrach, G., Subtil, J.C., Iglesias-García, J., García-Guix, M., Barturen Barroso, A., Gimeno-García, A.Z., Esteban, J.M., Pardo Balteiro, A., Velasco-Guardado, A., Vazquez-Sequeiros, E., Loras, C., Martínez-Moreno, B., Castellot, A., Huertas, C., Martínez-Lapiedra, M., Sánchez-Yague, A., Teran, A., Morales-Alvarado, V.J., Betes, M., de la Iglesia, D., Sánchez-Montes, C., Lozano, M.D., Lariño-Noia, J., Gines, A., Tebe, C. & Gornals, J. (2019). EUS-guided tissue acquisition in the study of the adrenal glands: Results of a nationwide multicenter study. PLoS ONE, 14(6), 1-16. doi: 10.1371/journal.pone.0216658 | - |
dc.identifier.issn | 1932-6203MIAR | - |
dc.identifier.uri | http://hdl.handle.net/10609/101699 | - |
dc.description.abstract | Background: There are limited data about the role of endoscopic ultrasound-guided tissue acquisition (EUS-TA), by fine needle aspiration (EUS-FNA) or biopsy (EUS-FNB), in the evaluation of the adrenal glands (AG). The primary aim was to assess the diagnostic yield and safety. The secondary aims were the malignancy predictors, and to create a predictive model of malignancy. Methods: This was a retrospective nationwide study involving all Spanish hospitals experienced in EUS-TA of AGs. Inclusion period was from April-2003 to April-2016. Inclusion criteria: all consecutive cases that underwent EUS-TA of AGs. EUS and cytopathology findings were evaluated. Statistical analyses: diagnostic accuracy of echoendoscopist's suspicion using cytology by EUS-TA, as gold standard; multivariate logistic regression model to predict tumor malignancy. Results: A total of 204 EUS-TA of AGs were evaluated. Primary tumor locations were lung 70%, others 19%, and unknown 11%. AG samples were adequate for cytological diagnosis in 91%, and confirmed malignancy in 60%. Diagnostic accuracy of the endosonographer's suspicion was 68%. The most common technique was: a 22-G (65%) and cytological needle (75%) with suction-syringe (66%). No serious adverse events were described. The variables most associated with malignancy were size>30mm (OR2.27; 95%CI, 1.16-4.05), heterogeneous echo-pattern (OR2.11; 95%CI, 1.1-3.9), variegated AG shape (OR2.46; 95%CI, 1-6.24), and endosonographer suspicion (OR17.46; 95%CI, 6.2-58.5). The best variables for a predictive multivariate logistic model of malignancy were age, sex, echo-pattern, and AG-shape. Conclusions: EUS-TA of the AGs is a safe, minimally invasive procedure, allowing an excellent diagnostic yield. These results suggest the possibility of developing a pre-EUS procedure predictive malignancy model. | en |
dc.language.iso | eng | - |
dc.publisher | PLoS ONE | - |
dc.relation.uri | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0216658&type=printable | - |
dc.rights | cc-by | - |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/es/ | - |
dc.subject | Endoscopic ultrasonography | en |
dc.subject | Diagnosis | en |
dc.subject | Ecografía endoscópica | es |
dc.subject | Diagnóstico | es |
dc.subject.lcsh | Endoscopic ultrasonography | en |
dc.subject.lcsh | Drainage | en |
dc.subject.lcsh | Surgical | en |
dc.title | EUS-guided tissue acquisition in the study of the adrenal glands: Results of a nationwide multicenter study | - |
dc.type | info:eu-repo/semantics/article | - |
dc.subject.lemac | Endoscopis | ca |
dc.subject.lcshes | Ecografía endoscópica | es |
dc.subject.lcshes | Drenaje quirúrgico | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.doi | 10.1371/journal.pone.0216658 | - |
dc.gir.id | AR/0000007183 | - |
dc.type.version | info:eu-repo/semantics/publishedVersion | - |
Appears in Collections: | Articles Articles cientÍfics |
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File | Description | Size | Format | |
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EUS_guided.pdf | 1,33 MB | Adobe PDF | View/Open |
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